Introduction to Bioinformatics using NGS data
Description
This intense one-week workshop provides an introduction to the analysis of next generation sequencing data. Lectures on the theory of concepts will be paired with practical computational exercises in the Linux environment. The practical exercises will focus on data from the Illumina platform, but we will discuss other sequencing platforms and the advantages and challenges to using their data during the lectures.
Briefly, the workshop covers the followings major topics:
- Working on the UNIX/LINUX command line
- Bioinformatic/NGS data formats and QC
- DNA variant calling workflow essentials
- RNA sequence analysis workflow essentials
Upcoming Training Instances
Introduction to Bioinformatics using NGS data
April 19, 2027 09:00 – April 23, 2027 17:00
Content Providers
Learning Outcomes
After this workshop you should be able to:
- Describe the basic principles of next generation sequencing.
- Use the Linux command line interface to manage simple file processing operations, and organise directory structures.
- Connect to and work on a remote compute cluster.
- Apply programs in Linux for analysis of NGS data.
- Summarise the applications of current NGS technologies, including the weakness and strengths of the approaches and when it is appropriate to use which one of them.
- Explain common NGS file formats.
- Interpret quality control of NGS reads.
- Explain the steps involved in variant calling using whole genome sequencing data.
- Independently perform a basic variant calling workflow on example data.
- Explain the steps involved in a differential gene expression workflow using RNA seq data.
- Hands-on experience with handling of raw RNA sequencing data, QC and quantification of gene expression.
- Conceptual understanding of differential gene expression analysis.
Structure & Duration
5 days contiguously Mon-Fri, 09:00 to 17:00 everyday except Fri when it's 09:00 to 15:00.
Prerequisites & Technical Requirements
Prior Knowledge
Have a background in genetics, cell biology, biomedicine, biochemistry, bioinformatics or comparable.
To get the maximum benefit from the workshop you should have a research project where you are currently using or are planning to use next generation sequencing.
Technical Requirements
No bioinformatics background is required. You should be able to use a computer.
Audience & Keywords
Target Audience
Keywords
Course Team
Past Course Instances
Introduction to Bioinformatics using NGS data
March 02, 2026 09:00 – March 06, 2026 17:00
Introduction to bioinformatics using NGS data
November 17, 2025 09:00 – November 21, 2025 17:00
Introduction to bioinformatics using NGS data – ONLINE
March 24, 2025 09:00 – March 28, 2025 17:00
Introduction to bioinformatics using NGS data
November 24, 2024 09:00 – November 29, 2024 17:00
Introduction to bioinformatics using NGS data – ONLINE
March 18, 2024 09:00 – March 22, 2024 17:00
Activity log
